TRF2 antibody

Catalog No. ABIN540901

Product Details anti-TRF2 Antibody

Target: TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))

Reactivity: Please inquire

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRF2 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP)

Purpose: Rabbit polyclonal antibody raised against recombinant TERF2.

Immunogen: Recombinant protein corresponding to TERF2.

Application Details

Application Notes: Western Blot (1:2000-1:5000)
Immunocytochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In Tris-glycine, 150 mM NaCl (0.1 % BSA, 0.05 % sodium azide)

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-TRF2 antibody (ABIN540901)

Hockemeyer, Palm, Else, Daniels, Takai, Ye, Keegan, de Lange, Hammer: "Telomere protection by mammalian Pot1 requires interaction with Tpp1." in: Nature structural & molecular biology, Vol. 14, Issue 8, pp. 754-61, (2007) (PubMed).

van Overbeek, de Lange: "Apollo, an Artemis-related nuclease, interacts with TRF2 and protects human telomeres in S phase." in: Current biology : CB, Vol. 16, Issue 13, pp. 1295-302, (2006) (PubMed).

Dimitrova, de Lange: "MDC1 accelerates nonhomologous end-joining of dysfunctional telomeres." in: Genes & development, Vol. 20, Issue 23, pp. 3238-43, (2006) (PubMed).

Celli, de Lange: "DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion." in: Nature cell biology, Vol. 7, Issue 7, pp. 712-8, (2005) (PubMed).

Ye, Donigian, van Overbeek, Loayza, Luo, Krutchinsky, Chait, de Lange: "TIN2 binds TRF1 and TRF2 simultaneously and stabilizes the TRF2 complex on telomeres." in: The Journal of biological chemistry, Vol. 279, Issue 45, pp. 47264-71, (2004) (PubMed).

Target Details for TRF2

Target: TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))

Alternative Name: TERF2 (TERF2 Products)

Synonyms: TERF2 antibody, TRBF2 antibody, TRF2 antibody, trf2 antibody, telomeric repeat binding factor 2 antibody, telomeric repeat binding factor 2 L homeolog antibody, TERF2 antibody, Terf2 antibody, terf2.L antibody

Pathways: Cell Division Cycle, Telomere Maintenance