TARDBP antibody (Internal Region)

Catalog No. ABIN541624

Product Details anti-TARDBP Antibody

Target: TARDBP (TAR DNA Binding Protein (TARDBP))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TARDBP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of TARDBP.

Specificity: At least two isoforms are known to exist for this protein, this TDP43 antibody only recongizes the longer of the two isoforms.

Cross-Reactivity: Human, Mouse, Rat

Immunogen: A synthetic peptide corresponding to 18 amino acids near internal region of human TARDBP.

Application Details

Application Notes: Western Blot (0.5-2 μg/mL)
Immunocytochemistry (5 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: In PBS (0.02 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-TARDBP antibody (ABIN541624)

Neumann, Sampathu, Kwong, Truax, Micsenyi, Chou, Bruce, Schuck, Grossman, Clark, McCluskey, Miller, Masliah, Mackenzie, Feldman, Feiden, Kretzschmar, Trojanowski, Lee: "Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis." in: Science (New York, N.Y.), Vol. 314, Issue 5796, pp. 130-3, (2006) (PubMed).

Buratti, Dörk, Zuccato, Pagani, Romano, Baralle: "Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping." in: The EMBO journal, Vol. 20, Issue 7, pp. 1774-84, (2001) (PubMed).

Target Details for TARDBP

Target: TARDBP (TAR DNA Binding Protein (TARDBP))

Alternative Name: TARDBP (TARDBP Products)

Synonyms: TARDBP antibody, TDP43 antibody, DKFZp459I2127 antibody, tardbp antibody, ALS10 antibody, TDP-43 antibody, 1190002A23Rik antibody, C85084 antibody, Tdp43 antibody, wu:fb77f02 antibody, wu:fc52g10 antibody, TAR DNA binding protein antibody, Tardbp protein antibody, TAR DNA binding protein L homeolog antibody, TAR DNA-binding protein 43-like antibody, TARDBP antibody, tardbp antibody, tardbp.L antibody, Tardbp antibody, LOC100621383 antibody

Gene ID: 23435

Pathways: Positive Regulation of Peptide Hormone Secretion