PPP3CA antibody (Protein Phosphatase 3, Catalytic Subunit, alpha Isoform)

Details for Product anti-PPP3CA Antibody No. ABIN543121
Target
Reactivity
Human
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40
38
23
12
11
7
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4
2
2
2
2
1
1
1
1
Host
Rabbit
67
16
2
1
Clonality
Polyclonal
Conjugate
This PPP3CA antibody is un-conjugated
3
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
77
40
22
18
14
6
5
3
2
2
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2
1
Options
Purpose Rabbit polyclonal antibody raised against synthetic peptide of PPP3CA.
Immunogen A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human PPP3CA.
Target
Alternative Name PPP3CA / Calcineurin A (PPP3CA Antibody Abstract)
Pathways RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Synaptic Membrane, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, VEGF Signaling
Application Notes Western Blot (1:1000)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
Restrictions For Research Use only
Buffer In PBS (0.09 % sodium azide)
Storage 4 °C,-20 °C
Storage Comment Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Images
Image no. 1 for anti-Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA) antibody (ABIN543121) Formalin-fixed and paraffin-embedded human cancer tissue reacted with PPP3CA polyclon...
Image no. 2 for anti-Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA) antibody (ABIN543121) Western blot analysis of PPP3CA polyclonal antibody in mouse kidney tissue lysate. P...
Product cited in: Rodríguez, Martínez-Martínez, López-Maderuelo, Ortega-Pérez, Redondo: "The linker region joining the catalytic and the regulatory domains of CnA is essential for binding to NFAT." in: The Journal of biological chemistry, Vol. 280, Issue 11, pp. 9980-4, 2005 (PubMed).

Shirane, Nakayama: "Inherent calcineurin inhibitor FKBP38 targets Bcl-2 to mitochondria and inhibits apoptosis." in: Nature cell biology, Vol. 5, Issue 1, pp. 28-37, 2003 (PubMed).

Bengoechea-Alonso, Pelacho, Osés-Prieto, Santiago, López-Moratalla, López-Zabalza: "Regulation of NF-kappaB activation by protein phosphatase 2B and NO, via protein kinase A activity, in human monocytes." in: Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society, Vol. 8, Issue 1, pp. 65-74, 2003 (PubMed).