GJB2 antibody (AA 1-16)

Catalog No. ABIN548512

Product Details anti-GJB2 Antibody

Target: GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))

Binding Specificity: AA 1-16

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GJB2 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit polyclonal antibody raised against partial synthetic peptide of human GJB2.

Sequence: MDWGTLQTIL GGVNKH

Cross-Reactivity: Human, Mouse, Rat

Immunogen: A synthetic peptide corresponding to amino acids 1-16 of human GJB2.

Isotype: IgG

Application Details

Application Notes: Western Blot (0.1-0.5 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from 0.2 mg Na₂HPO₄, 0.9 mg NaCl (0.05 mg Thimerosal, 0.05 mg sodium azide, 5 mg BSA).

Preservative: Sodium azide, Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C.
After reconstitution with 0.2 mL of distilled water and concentration will be 500 ug/mL, store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-GJB2 antibody (ABIN548512)

Djalilian, McGaughey, Patel, Seo, Yang, Cheng, Tomic, Sinha, Ishida-Yamamoto, Segre: "Connexin 26 regulates epidermal barrier and wound remodeling and promotes psoriasiform response." in: The Journal of clinical investigation, Vol. 116, Issue 5, pp. 1243-53, (2006) (PubMed).

Abe, Kelley, Kimberling, Usami: "Connexin 26 gene (GJB2) mutation modulates the severity of hearing loss associated with the 1555A-->G mitochondrial mutation." in: American journal of medical genetics, Vol. 103, Issue 4, pp. 334-8, (2001) (PubMed).

Target Details for GJB2

Target: GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))

Alternative Name: GJB2 / Cx26 (GJB2 Products)

Synonyms: ppk antibody, cx26 antibody, dfna3 antibody, dfnb1 antibody, nsrd1 antibody, dfna3a antibody, dfnb1a antibody, MGC53062 antibody, connexin-26 antibody, GJB2 antibody, AI325222 antibody, Cnx26 antibody, Cx26 antibody, Gjb-2 antibody, CXN-26 antibody, CX26 antibody, DFNA3 antibody, DFNA3A antibody, DFNB1 antibody, DFNB1A antibody, HID antibody, KID antibody, NSRD1 antibody, PPK antibody, gap junction protein beta 2 L homeolog antibody, gap junction protein beta 2 antibody, gap junction protein, beta 2 antibody, gjb2.L antibody, GJB2 antibody, Gjb2 antibody

Gene ID: 2706

Pathways: Sensory Perception of Sound, Cell-Cell Junction Organization