TLR4 antibody (AA 970-1000)

Catalog No. ABIN549529

Product Details anti-TLR4 Antibody

Target: TLR4 (Toll-Like Receptor 4 (TLR4))

Binding Specificity: AA 970-1000

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLR4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Dot Blot (DB)

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of TLR4.

Cross-Reactivity: Human

Immunogen: A synthetic peptide corresponding to amino acids 970-1000 of human TLR4.

Application Details

Application Notes: ELISA (1:20000)
Dot Blot (1:20000)
Western Blot (1:500)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In buffer containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-TLR4 antibody (ABIN549529)

Oshiumi, Matsumoto, Funami, Akazawa, Seya: "TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction." in: Nature immunology, Vol. 4, Issue 2, pp. 161-7, (2003) (PubMed).

Fitzgerald, Rowe, Barnes, Caffrey, Visintin, Latz, Monks, Pitha, Golenbock: "LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF." in: The Journal of experimental medicine, Vol. 198, Issue 7, pp. 1043-55, (2003) (PubMed).

Oshiumi, Sasai, Shida, Fujita, Matsumoto, Seya: "TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to toll-like receptor 4 TICAM-1 that induces interferon-beta." in: The Journal of biological chemistry, Vol. 278, Issue 50, pp. 49751-62, (2003) (PubMed).

Target Details for TLR4

Target: TLR4 (Toll-Like Receptor 4 (TLR4))

Alternative Name: CD284 / TLR4 (TLR4 Products)

Synonyms: ARMD10 antibody, CD284 antibody, TLR-4 antibody, TOLL antibody, Lps antibody, Ly87 antibody, Ran/M1 antibody, Rasl2-8 antibody, toll like receptor 4 antibody, toll-like receptor 4 antibody, TLR4 antibody, Tlr4 antibody

Gene ID: 7099

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins