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NR1H4 antibody (N-Term)
NR1H4
Reactivity: Human, Rat, Mouse, Dog, Horse, Cow, Rabbit, Pig
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-NR1H4 Antibody
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Target
See all NR1H4 Antibodies
NR1H4
(Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))
Binding Specificity
All epitopes for NR1H4 antibodies
N-Term
Reactivity
All reactivities for NR1H4 antibodies
Human, Rat, Mouse, Dog, Horse, Cow, Rabbit, Pig
Host
All hosts for NR1H4 antibodies
Rabbit
Clonality
All clonalities for NR1H4 antibodies
Polyclonal
Conjugate
All conjugates for NR1H4 antibodies
This NR1H4 antibody is un-conjugated
Application
All applications for NR1H4 antibodies
Western Blotting (WB)
Sequence
VAGPLGQNLE VEPYSQYSNV QFPQVQPQIS SSSYYSNLGF YPQQPEEWYS
Predicted Reactivity
Cow: 93%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%
Characteristics
This is a rabbit polyclonal antibody against NR1H4. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of human NR1H4
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Discover our top product NR1H4 Primary Antibody
Alternatives
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anti-Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4) (Middle Region) antibody
NR1H4
Reactivity: Human, Rat, Mouse, Dog, Horse, Cow, Rabbit, Guinea Pig
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
anti-Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4) (AA 175-280) antibody
NR1H4
Reactivity: Human, Rat, Mouse
WB, ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
anti-Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4) (AA 194-243) antibody
NR1H4
Reactivity: Human, Rat, Mouse, Dog, Horse, Cow, Pig, Guinea Pig, Monkey, Bat
WB, IHC, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for NR1H4
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Target
NR1H4
(Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))
Alternative Name
NR1H4 (NR1H4 Products )
Synonyms
zgc:110190 antibody, zgc:92742 antibody, NR1H4 antibody, BAR antibody, FXR antibody, HRR-1 antibody, HRR1 antibody, RIP14 antibody, AI957360 antibody, Fxr antibody, Rxrip14 antibody, nuclear receptor subfamily 1, group H, member 5 S homeolog antibody, nuclear receptor subfamily 1, group H, member 4 antibody, nuclear receptor subfamily 1 group H member 4 antibody, nr1h5.S antibody, nr1h4 antibody, NR1H4 antibody, Nr1h4 antibody
Background
This gene encodes a ligand-activated transcription factor that shares structural features in common with nuclear hormone receptor family members. This protein functions as a receptor for bile acids, and when bound to bile acids, binds to DNA and regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described. Alias Symbols: BAR, FXR, HRR1, HRR-1, RIP14 Protein Size: 270
Gene ID
9971
NCBI Accession
NM_001206977 , NP_001193906
UniProt
Q96RI1
Pathways
Nuclear Receptor Transcription Pathway , Steroid Hormone Mediated Signaling Pathway , Regulation of Carbohydrate Metabolic Process
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