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MCL-1 antibody (Middle Region)
MCL1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MCL-1 Antibody
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Target
See all MCL-1 (MCL1) Antibodies
MCL-1 (MCL1)
(Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))
Binding Specificity
All epitopes for MCL-1 antibodies
Middle Region
Reactivity
All reactivities for MCL-1 antibodies
Human
Host
All hosts for MCL-1 antibodies
Rabbit
Clonality
All clonalities for MCL-1 antibodies
Polyclonal
Conjugate
All conjugates for MCL-1 antibodies
This MCL-1 antibody is un-conjugated
Application
All applications for MCL-1 antibodies
Western Blotting (WB)
Sequence
EELDGYEPEP LGKRPAVLPL LELVGESGNN TSTDGSLPST PPPAEEEEDE
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human MCL1
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for MCL-1
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Target
MCL-1 (MCL1)
(Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))
Alternative Name
MCL1 (MCL1 Products )
Synonyms
BCL2L3 antibody, EAT antibody, MCL1-ES antibody, MCL1L antibody, MCL1S antibody, Mcl-1 antibody, TM antibody, bcl2-L-3 antibody, mcl1/EAT antibody, AW556805 antibody, mcl-1 antibody, fb72f02 antibody, wu:fb70a08 antibody, wu:fb72f02 antibody, zfMLP1 antibody, zfMcl-1a antibody, zgc:109835 antibody, zgc:109763 antibody, E3 antibody, E3-2 antibody, RNE3 antibody, RNU107 antibody, SNORA63A antibody, elF-4AII antibody, MCL1, BCL2 family apoptosis regulator antibody, myeloid cell leukemia sequence 1 antibody, MCL1, BCL2 family apoptosis regulator a antibody, MCL1, BCL2 family apoptosis regulator b antibody, small nucleolar RNA, H/ACA box 63 antibody, MCL1 antibody, Mcl1 antibody, mcl1a antibody, mcl1b antibody, SNORA63 antibody
Background
This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. Alias Symbols: TM, EAT, MCL1L, MCL1S, Mcl-1, BCL2L3, MCL1-ES, bcl2-L-3, mcl1/EAT Protein Size: 271
Gene ID
4170
NCBI Accession
NM_001197320 , NP_001184249
Pathways
MAPK Signaling
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