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LAT antibody (Middle Region)

LAT Reactivity: Human WB Host: Rabbit Polyclonal unconjugated

Catalog No. ABIN5514915

Datasheet as PDF

Target See all LAT Antibodies

LAT (Linker For Activation of T Cells (LAT))
Binding Specificity
18

15

15

8

7

7

7

4

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Middle Region
Reactivity
120

56

40

1
Human
Host
113

7

2

1
Rabbit
Compatible Secondaries
Clonality
116

7
Polyclonal
Conjugate
58

7

6

6

6

6

6

6

4

3

3

3

3

3

3
This LAT antibody is un-conjugated
Application
68

40

39

39

15

11

9

9

4

2

1

1
Western Blotting (WB)

Sequence

LPIPRSPQPL GGSHRTPSSR RDSDGANSVA SYENEGASGI RGAQAGWGVW

Purification

Affinity purified

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human LAT

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anti-Linker For Activation of T Cells (LAT) antibody
LAT Reactivity: Human, Mouse, Rat WB, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Linker For Activation of T Cells (LAT) (Cytoplasmic Domain) antibody
LAT Reactivity: Human WB, IP, FACS Host: Mouse Monoclonal LAT-01 unconjugated

anti-Linker For Activation of T Cells (LAT) (pTyr191) antibody
LAT Reactivity: Human WB, ELISA, IHC, IP, IF Host: Rabbit Monoclonal 2E4 unconjugated Recombinant Antibody

anti-Linker For Activation of T Cells (LAT) (AA 1-233) antibody
LAT Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 3B11-1D5 unconjugated

anti-Linker For Activation of T Cells (LAT) (AA 30-237) antibody
LAT Reactivity: Mouse WB, IHC, ICC Host: Rabbit Polyclonal unconjugated

anti-Linker For Activation of T Cells (LAT) (pTyr161) antibody
LAT Reactivity: Human ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-Linker For Activation of T Cells (LAT) (AA 25-221) antibody
LAT Reactivity: Human WB, IHC, ICC Host: Rabbit Polyclonal unconjugated

anti-Linker For Activation of T Cells (LAT) (AA 33-227) antibody
LAT Reactivity: Rat WB, IHC, ICC Host: Rabbit Polyclonal unconjugated

anti-Linker For Activation of T Cells (LAT) (Tyr255) antibody
LAT Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated

anti-Linker For Activation of T Cells (LAT) (Tyr659) antibody
LAT Reactivity: Human, Mouse, Rat WB, ELISA Host: Rabbit Polyclonal unconjugated

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Format

Liquid

Buffer

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

-20 °C

Storage Comment

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target

LAT (Linker For Activation of T Cells (LAT))

Alternative Name

LAT (LAT Products)

Synonyms

LAT antibody, lat antibody, LAT1 antibody, pp36 antibody, linker for activation of T-cells antibody, linker for activation of T cells antibody, LAT antibody, lat antibody, Lat antibody

Background

The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alias Symbols: LAT1, pp36

Protein Size: 262

Gene ID

27040

NCBI Accession

NM_001014987, NP_001014987

UniProt

O43561

Pathways

TCR Signaling, Fc-epsilon Receptor Signaling Pathway