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TRIB3 antibody (N-Term)
TRIB3
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-TRIB3 Antibody
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Target
See all TRIB3 Antibodies
TRIB3
(Tribbles Homolog 3 (Drosophila) (TRIB3))
Binding Specificity
All epitopes for TRIB3 antibodies
N-Term
Reactivity
All reactivities for TRIB3 antibodies
Human
Host
All hosts for TRIB3 antibodies
Rabbit
Clonality
All clonalities for TRIB3 antibodies
Polyclonal
Conjugate
All conjugates for TRIB3 antibodies
This TRIB3 antibody is un-conjugated
Application
All applications for TRIB3 antibodies
Western Blotting (WB)
Sequence
PLAAPAGSLS RKKRLELDDN LDTERPVQKR ARSGPQPRLP PCLLPLSPPT
Characteristics
This is a rabbit polyclonal antibody against TRIB3. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human TRIB3
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for TRIB3
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Target
TRIB3
(Tribbles Homolog 3 (Drosophila) (TRIB3))
Alternative Name
TRIB3 (TRIB3 Products )
Synonyms
zgc:76966 antibody, TRIB3 antibody, C20orf97 antibody, NIPK antibody, SINK antibody, SKIP3 antibody, TRB3 antibody, Ifld2 antibody, Nipk antibody, TRB-3 antibody, Trb3 antibody, tribbles pseudokinase 3 antibody, trib3 antibody, TRIB3 antibody, Trib3 antibody
Background
The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. Alias Symbols: TRIB3, C20orf97, NIPK, SKIP3, TRB3, Protein Interaction Partner: RPGRIP1, UBC, DDIT3, ATF4, RFWD2, PRMT5, AKT1, APP, SMURF1, CDC25A, BMPR2, SMAD3, BCL6, COPS6, RBM48, EEF1G, SETDB1, GIT1, GDF9, KAT5, AKT2, RELA, ATF5, HRSP12, TIAF1, MCM3AP, LTBP4, SIAH1, RBM4, PSMA3, RPSA, HLA-B, GRN, FN1, CSNK2B, Protein Size: 358
Gene ID
57761
NCBI Accession
XP_005260831
UniProt
Q96RU7
Pathways
Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Regulation of Lipid Metabolism by PPARalpha
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