UPK1A antibody (Middle Region)

Catalog No. ABIN5515448

Product Details anti-UPK1A Antibody

Target: UPK1A (Uroplakin 1a (UPK1A))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UPK1A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TKQMLTFYSA DTDQGQELTR LWDRVMIEQE CCGTSGPMDW VNFTSAFRAA

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human UPK1A

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for UPK1A

Target: UPK1A (Uroplakin 1a (UPK1A))

Alternative Name: UPK1A (UPK1A Products)

Synonyms: up1a antibody, upia antibody, upka antibody, tspan21 antibody, MGC81390 antibody, upk1a antibody, MGC69509 antibody, UPK1A antibody, wu:fb14a02 antibody, wu:fk84c04 antibody, zgc:136832 antibody, TSPAN21 antibody, UP1A antibody, UPIA antibody, UPKA antibody, 1110031P12Rik antibody, AU019298 antibody, C87192 antibody, Tspan21 antibody, Upk1 antibody, uroplakin 1A antibody, uroplakin 1A L homeolog antibody, uroplakin 1a antibody, UPK1A antibody, upk1a.L antibody, upk1a antibody, Upk1a antibody

Background: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression. Alternative splicing results in multiple transcript variants of this gene.

Alias Symbols: UP1A, UPIA, UPKA, TSPAN21

Protein Size: 167

Gene ID: 11045

NCBI Accession: NM_001281443, NP_001268372

UniProt: O00322