MARK2 antibody (C-Term)

Catalog No. ABIN5516100

Product Details anti-MARK2 Antibody

Target: MARK2 (MAP/microtubule Affinity-Regulating Kinase 2 (MARK2))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARK2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IPTSNSYSKK TQSNNAENKR PEEDRESGRK ASSTAKVPAS PLPGLERKKT

Characteristics: This is a rabbit polyclonal antibody against MARK2. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human MARK2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MARK2

Target: MARK2 (MAP/microtubule Affinity-Regulating Kinase 2 (MARK2))

Alternative Name: MARK2 (MARK2 Products)

Synonyms: EMK-1 antibody, EMK1 antibody, PAR-1 antibody, Par-1b antibody, Par1b antibody, AU024026 antibody, Emk antibody, Par-1 antibody, mKIAA4207 antibody, microtubule affinity regulating kinase 2 antibody, MAP/microtubule affinity regulating kinase 2 antibody, MARK2 antibody, Mark2 antibody

Background: This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: MARK2 {ECO:0000312|EMBL:AAH08771.2, , EMK1

Protein Interaction Partner: Crtc2, MAPT, CDKN1A, BAIAP2, CEP57, AURKB, CAMK1, UBC, RNF41, YWHAQ, YWHAB, PARD3, YWHAE, GAB1, GAB2, VCP, KIF13B, PRKCE, PKD1, DMD, RHOA, PINK1, ARHGEF2, YWHAG, UTRN, PRKCI, PPP2R4, RAB11FIP2, USP21, STK11, MARK2, NEDD4L, NEDD4, PARD6G, PARD6A, MTCL1, YW

Protein Size: 788

Gene ID: 2011

UniProt: Q7KZI7

Pathways: SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection