×
For best experience we recommend to activate Javascript in your browser.
SIGLEC8 antibody (Middle Region)
SIGLEC8
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-SIGLEC8 Antibody
(hide)
Target
See all SIGLEC8 Antibodies
SIGLEC8
(Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
Binding Specificity
All epitopes for SIGLEC8 antibodies
Middle Region
Reactivity
All reactivities for SIGLEC8 antibodies
Human
Host
All hosts for SIGLEC8 antibodies
Rabbit
Clonality
All clonalities for SIGLEC8 antibodies
Polyclonal
Conjugate
All conjugates for SIGLEC8 antibodies
This SIGLEC8 antibody is un-conjugated
Application
All applications for SIGLEC8 antibodies
Western Blotting (WB)
Sequence
VRSCRKKSAR PAAGVGDTGM EDAKAIRGSA SQGPLTESWK DGNPLKKPPP
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human SIGLEC8
Top Product
Discover our top product SIGLEC8 Primary Antibody
Alternatives
(show)
Application Details
(hide)
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
(hide)
Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for SIGLEC8
(hide)
Target
SIGLEC8
(Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
Alternative Name
SIGLEC8 (SIGLEC8 Products )
Synonyms
SAF2 antibody, SIGLEC-8 antibody, SIGLEC8L antibody, SIGLEC8 antibody, sialic acid binding Ig like lectin 8 antibody, sialic acid-binding Ig-like lectin 8 antibody, SIGLEC8 antibody, LOC506364 antibody
Background
Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM, MIM 603492) that mediates an association with SLAM-associated protein (SAP, MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).[supplied by OMIM, May 2010] Alias Symbols: SAF2, SIGLEC-8, SIGLEC8L Protein Size: 201
Gene ID
27181
NCBI Accession
NM_014442 , NP_055257
UniProt
Q9NYZ4
Recently viewed
(hide)