COPS6 antibody (C-Term)
-
- Target See all COPS6 Antibodies
- COPS6 (COP9 Signalosome Complex Subunit 6 (COPS6))
-
Binding Specificity
- C-Term
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This COPS6 antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Sequence
- LILEYVKASE AGEVPFNHEI LREAYALCHC LPVLSTDKFK TDFYDQCNDV
- Characteristics
- This is a rabbit polyclonal antibody against COPS6. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human COPS6
- Top Product
- Discover our top product COPS6 Primary Antibody
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- COPS6 (COP9 Signalosome Complex Subunit 6 (COPS6))
- Alternative Name
- COPS6 (COPS6 Products)
- Synonyms
- CG6932 antibody, CH6 antibody, Csn6 antibody, Dch6 antibody, Dmel\\CG6932 antibody, zgc:112075 antibody, Sgn3 antibody, VIP/MOV34 antibody, CSN6 antibody, MOV34-34KD antibody, COP9 signalosome subunit 6 antibody, COP-9 SigNalosome subunit antibody, COPS6 antibody, Cops6 antibody, CSN6 antibody, cops6 antibody, csn-6 antibody
- Background
-
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr.
Alias Symbols: Name=COPS6,
Protein Interaction Partner: NEDD8, CUL1, UBC, COPS5, GPS1, SUMO1, POP7, COPS7B, COPS7A, CUL4B, USP7, COPS4, FBXO6, FBXW4, IGHV3OR15-7, vpr, TP63, RFWD2, SFN, IRF5, COPS8, COPS2, COPS3, DDB2, DDB1, ERCC8, TOR1AIP2, LRR1, RBX1, VPRBP, LRRC14, CUL2, CUL3, CUL4A, CUL5, TCEB2, TCEB1, SKP
Protein Size: 327 - Gene ID
- 10980
- NCBI Accession
- NP_006824
- UniProt
- Q7L5N1
- Pathways
- Cell Division Cycle
-