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IL12A antibody (Middle Region)
IL12A
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-IL12A Antibody
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Target
See all IL12A Antibodies
IL12A
(Interleukin 12 alpha (IL12A))
Binding Specificity
All epitopes for IL12A antibodies
Middle Region
Reactivity
All reactivities for IL12A antibodies
Human
Host
All hosts for IL12A antibodies
Rabbit
Clonality
All clonalities for IL12A antibodies
Polyclonal
Conjugate
All conjugates for IL12A antibodies
This IL12A antibody is un-conjugated
Application
All applications for IL12A antibodies
Western Blotting (WB)
Sequence
SNMLQKARQT LEFYPCTSEE IDHEDITKDK TSTVEACLPL ELTKNESCLN
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human IL12A
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 23 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for IL12A
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Target
IL12A
(Interleukin 12 alpha (IL12A))
Alternative Name
IL12A (IL12A Products )
Synonyms
CLMF antibody, IL-12A antibody, NFSK antibody, NKSF1 antibody, P35 antibody, CLMF2 antibody, IL-12B antibody, NKSF antibody, NKSF2 antibody, p40 antibody, Il-12b antibody, Il12p40 antibody, Il-12p40 antibody, Il12 antibody, IL-12p40 antibody, IL-12p35 antibody, Il-12a antibody, Ll12a antibody, p35 antibody, IL12p35 antibody, Il-12 p35 antibody, IL12p40 antibody, IL12 antibody, IL-12 p35 antibody, interleukin 12A antibody, interleukin 12B antibody, interleukin 12b antibody, interleukin 12a antibody, Interleukin 12 level antibody, IL12A antibody, IL12B antibody, Il12b antibody, Il12a antibody, IL12 antibody, il12a antibody
Background
This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. Alias Symbols: P35, CLMF, NFSK, NKSF1, IL-12A, Protein Size: 219
Gene ID
3592
NCBI Accession
NM_000882 , NP_000873
UniProt
P29459
Pathways
JAK-STAT Signaling , Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Activated T Cell Proliferation
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