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OAS3 antibody (C-Term)

OAS3 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5530213
  • Target See all OAS3 Antibodies
    OAS3 (2'-5' Oligoadenylate Synthetase 3 (OAS3))
    Binding Specificity
    • 15
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    AA 1056-1087, C-Term
    Reactivity
    • 34
    • 16
    • 2
    Human
    Host
    • 33
    • 1
    Rabbit
    Clonality
    • 34
    Polyclonal
    Conjugate
    • 11
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This OAS3 antibody is un-conjugated
    Application
    • 29
    • 15
    • 13
    • 13
    • 4
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB)
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
    Immunogen
    This OAS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1056-1087 amino acids from the C-terminal region of human OAS3.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product OAS3 Primary Antibody
  • Application Notes
    For WB starting dilution is: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.56 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    OAS3 (2'-5' Oligoadenylate Synthetase 3 (OAS3))
    Alternative Name
    OAS3 (OAS3 Products)
    Synonyms
    p100 antibody, Oasl10 antibody, 2'-5'-oligoadenylate synthetase 3 antibody, 2'-5' oligoadenylate synthetase 3 antibody, OAS3 antibody, Oas3 antibody
    Background
    OAS3 is an interferon inducible protein that belongs to the 2-5A synthetase family, may play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. OAS3 synthesizes preferentially dimeric 2',5'-oligoadenylate molecules. GTP can be an alternative substrate. OAS3 binds double-stranded RNA and polymerizes ATP into PPP(A2'P5'A)N oligomers, which activate the latent RNase L that, when activated, cleaves single-stranded RNAs. The protein is present at high level in placenta trophoblast.
    Molecular Weight
    121 kDa
    Gene ID
    4940
    UniProt
    Q9Y6K5
    Pathways
    Hepatitis C
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