KARS antibody (N-Term)

Catalog No. ABIN5531489

Product Details anti-KARS Antibody

Target: KARS (Lysyl-tRNA Synthetase (KARS))

Binding Specificity: AA 70-98, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KARS antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This KARS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-98 amino acids from the N-terminal region of human KARS.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for KARS

Target: KARS (Lysyl-tRNA Synthetase (KARS))

Alternative Name: KARS (KARS Products)

Synonyms: CG12141 antibody, Dmel\\CG12141 antibody, KRS antibody, LysRS antibody, cb530 antibody, wu:fa16h02 antibody, zgc:92483 antibody, kars antibody, MGC53345 antibody, kars2 antibody, krs antibody, krs-1 antibody, KARS antibody, Tb06.28P18.190 antibody, CMTRIB antibody, DFNB89 antibody, KARS1 antibody, KARS2 antibody, AA589550 antibody, AL024334 antibody, AL033315 antibody, AL033367 antibody, D8Ertd698e antibody, D8Wsu108e antibody, mKIAA0070 antibody, Lysyl-tRNA synthetase antibody, lysyl-tRNA synthetase antibody, lysyl-tRNA synthetase S homeolog antibody, lysyl-tRNA synthetase L homeolog antibody, LysRS antibody, kars antibody, kars.S antibody, kars.L antibody, Bm1_16500 antibody, lysS antibody, Taci_1118 antibody, Tpau_1737 antibody, Arch_0261 antibody, Trad_2960 antibody, Spirs_3699 antibody, KARS antibody, LOC100280510 antibody, Tb927.6.1510 antibody, Kars antibody

Background: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 68 kDa

Gene ID: 3735

UniProt: Q15046