PCSK4 antibody (N-Term)

Catalog No. ABIN5531966

Product Details anti-PCSK4 Antibody

Target: PCSK4 (Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4))

Binding Specificity: AA 168-196, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCSK4 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PCSK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-196 amino acids from the N-terminal region of human PCSK4.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for PCSK4

Target: PCSK4 (Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4))

Alternative Name: PCSK4 (PCSK4 Products)

Synonyms: PC4 antibody, SPC5 antibody, AI647044 antibody, L21221 antibody, NEC 3 antibody, NEC3 antibody, PCSK4 antibody, pc4 antibody, spc5 antibody, MGC146505 antibody, pcsk4 antibody, proprotein convertase subtilisin/kexin type 4 antibody, proprotein convertase subtilisin/kexin type 4 L homeolog antibody, PCSK4 antibody, Pcsk4 antibody, pcsk4 antibody, pcsk4.L antibody

Background: Proprotein convertases, including PCSK4, are calcium-dependent serine proteases related to bacterial subtilisins and to yeast kexin. These enzymes process precursor proteins to their active forms by selective cleavage of the polypeptide at sites following paired basic amino acids. In mammals, this family comprises PC1 (MIM 162150), PC2 (MIM 162151), PC4, PC5 (MIM 600488), furin (FUR, MIM 136950), and PACE4 (MIM 167405). Substrates for these enzymes range from prohormones to precursors for growth factors to cell surface receptors and viral surface glycoproteins (Cao et al., 2001 [PubMed 11776387]).[supplied by OMIM].

Molecular Weight: 83 kDa

Gene ID: 54760

UniProt: Q6UW60