SKP1 antibody (AA 58-87)

Catalog No. ABIN5534676

Product Details anti-SKP1 Antibody

Target: SKP1 (S-Phase Kinase-Associated Protein 1 (SKP1))

Binding Specificity: AA 58-87

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SKP1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This SKP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-87 amino acids from the Central region of human SKP1.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SKP1

Target: SKP1 (S-Phase Kinase-Associated Protein 1 (SKP1))

Alternative Name: SKP1 (SKP1 Products)

Synonyms: EMC19 antibody, OCP-II antibody, OCP2 antibody, SKP1A antibody, TCEB1L antibody, p19A antibody, 15kDa antibody, 2610043E24Rik antibody, 2610206H23Rik antibody, SKP1 antibody, Tceb1l antibody, p19Skp1 antibody, Skp1a antibody, skp1a antibody, zgc:73186 antibody, ocp2 antibody, emc19 antibody, ocp-ii antibody, tceb1l antibody, ARABIDOPSIS SKP1 HOMOLOGUE 1 antibody, ASK1 antibody, ATSKP1 antibody, S phase kinase-associated protein 1 antibody, T4O12.17 antibody, T4O12_17 antibody, UFO INTERACTING PROTEIN 1 antibody, UIP1 antibody, ocp-2 antibody, S-phase kinase associated protein 1 antibody, S-phase kinase-associated protein 1 antibody, S-phase kinase-associated protein 1 pseudogene antibody, S-phase kinase-associated protein 1A antibody, S-phase kinase-associated protein 1 S homeolog antibody, S phase kinase-associated protein 1 antibody, SKP1 antibody, skp1 antibody, LOC100340043 antibody, Skp1a antibody, Skp1 antibody, skp1.S antibody

Background: SKP1A is an F-box protein which functions as a substrate recognition component of the SCF ubiquitin ligase complex. It binds to cyclin F, S-phase kinase-associated protein 2, and other regulatory proteins involved in ubiquitin proteolysis through an F-box motif. SKP1A also collaborates with a network of proteins to control beta-catenin levels and affects the activity level of beta-catenin dependent TCF transcription factors. Studies have also characterized the protein as an RNA polymerase II elongation factor.

Molecular Weight: 19 kDa

Gene ID: 6500

UniProt: P63208

Pathways: Cell Division Cycle, Hedgehog Signaling, Mitotic G1-G1/S Phases