FCGR3B antibody (N-Term)

Catalog No. ABIN5535582

Product Details anti-FCGR3B Antibody

Target: FCGR3B (Fc Fragment of IgG, Low Affinity IIIb, Receptor (CD16b) (FCGR3B))

Binding Specificity: AA 12-47, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FCGR3B antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FCGR3B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 12-47 amino acids from the N-terminal region of human FCGR3B.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for FCGR3B

Target: FCGR3B (Fc Fragment of IgG, Low Affinity IIIb, Receptor (CD16b) (FCGR3B))

Alternative Name: FCGR3B (FCGR3B Products)

Synonyms: CD16 antibody, CD16b antibody, FCG3 antibody, FCGR3 antibody, FCR-10 antibody, FCRIII antibody, FCRIIIb antibody, FcRIII antibody, Fc fragment of IgG receptor IIIb antibody, Fc receptor, IgG, low affinity III antibody, Fc fragment of IgG receptor IIIa antibody, Fc-gamma RIII antibody, FCGR3B antibody, Fcgr3 antibody, FCGR3A antibody, FCGR3 antibody

Background: Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.

Molecular Weight: 26 kDa

Gene ID: 2215

UniProt: O75015