PIM3 antibody (C-Term)

Catalog No. ABIN5537319

Product Details anti-PIM3 Antibody

Target: PIM3 (Pim-3 Oncogene (PIM3))

Binding Specificity: AA 259-288, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIM3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This PIM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-288 amino acids from the C-terminal region of human PIM3.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for PIM3

Target: PIM3 (Pim-3 Oncogene (PIM3))

Alternative Name: PIM3 (PIM3 Products)

Synonyms: pim1-a antibody, pim-3 antibody, BC026639 antibody, Kid1 antibody, Serine/threonine-protein kinase Pim-3 antibody, Pim-3 proto-oncogene, serine/threonine kinase S homeolog antibody, Pim-3 proto-oncogene, serine/threonine kinase antibody, pim-3 oncogene antibody, proviral integration site 3 antibody, pim3 antibody, pim3.S antibody, PIM3 antibody, Pim3 antibody

Background: PIM3 is a memberof the Ser/Thr protein kinase family that may be involved in cell cycle progression and anti-apoptosis process. This protein has been implicated in proliferation of human hepatoma cell lines. PIM3 is widely expressed, with the exception of no expression observed in colon, thymus, and small intestine. PIM3 is expressed in human hepatoma cell lines but not in normal liver tissues.

Molecular Weight: 36 kDa

Gene ID: 415116

UniProt: Q86V86

Pathways: Negative Regulation of Hormone Secretion