CTLA4 antibody (AA 36-161)
-
- Target See all CTLA4 Antibodies
- CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
-
Binding Specificity
- AA 36-161
-
Reactivity
- Human
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This CTLA4 antibody is un-conjugated
-
Application
- Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Neutralization (Neut)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human CD152 (AA: extra 36-161) expressed in E. coli.
- Clone
- 8B3F8
- Isotype
- IgG1
- Top Product
- Discover our top product CTLA4 Primary Antibody
-
-
- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
-
- Target
- CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
- Alternative Name
- CD152 (CTLA4 Products)
- Synonyms
- CTLA-4 antibody, CTLA4 antibody, CD152 antibody, Cd152 antibody, Ctla-4 antibody, Ly-56 antibody, CD antibody, CELIAC3 antibody, GRD4 antibody, GSE antibody, IDDM12 antibody, sCTLA4 antibody, cytotoxic T-lymphocyte associated protein 4 antibody, cytotoxic T-lymphocyte-associated protein 4 antibody, CTLA4 antibody, Ctla4 antibody
- Background
-
Description: This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.
Aliases: CTLA4, CD, GSE, GRD4, ALPS5, CTLA-4, IDDM12, CELIAC3
- Molecular Weight
- 24.6 kDa
- Gene ID
- 1493
- HGNC
- 1493
- Pathways
- Cancer Immune Checkpoints
-