ITPR1 antibody (AA 2470-2577)

Catalog No. ABIN561567

Product Details anti-ITPR1 Antibody

Target: ITPR1 (Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1))

Binding Specificity: AA 2470-2577

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ITPR1 antibody is un-conjugated

Application: ELISA

Purpose: Mouse monoclonal antibody raised against a partial recombinant ITPR1.

Sequence: EHTCETLLMC IVTVLSHGLR SGGGVGDVLR KPSKEEPLFA ARVIYDLLFF FMVIIIVLNL IFGVIIDTFA DLRSEKQKKE EILKTTCFIC GLERDKFDNK TVTFEEHI

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: ITPR1 (NP_002213, 2470 a.a. ~ 2577 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 2B6

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-ITPR1 antibody (ABIN561567)

Olson, Sandison, Chalmers, McCarron: "Microdomains of muscarinic acetylcholine and Ins(1,4,5)P? receptors create 'Ins(1,4,5)P? junctions' and sites of Ca²+ wave initiation in smooth muscle." in: Journal of cell science, Vol. 125, Issue Pt 22, pp. 5315-28, (2013) (PubMed).

Target Details for ITPR1

Target: ITPR1 (Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1))

Alternative Name: ITPR1 (ITPR1 Products)

Synonyms: D6Pas2 antibody, ENSMUSG00000072853 antibody, Gm10429 antibody, IP3R1 antibody, InsP3R antibody, Ip3r antibody, Itpr-1 antibody, P400 antibody, Pcp-1 antibody, Pcp1 antibody, opt antibody, I145TR antibody, InsP3R1 antibody, INSP3R1 antibody, IP3R antibody, SCA15 antibody, SCA16 antibody, SCA29 antibody, inositol 1,4,5-trisphosphate receptor type 1 antibody, inositol 1,4,5-trisphosphate receptor 1 antibody, inositol 1,4,5-trisphosphate receptor, type 1 antibody, ITPR1 antibody, Itpr1 antibody

Background: Full Gene Name: inositol 1,4,5-triphosphate receptor, type 1
Synonyms: INSP3R1,IP3R,IP3R1,SCA15,SCA16

Gene ID: 3708

NCBI Accession: NM_002222

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, Synaptic Membrane, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma