FOLR2
Reactivity: Human
FACS
Host: Rabbit
Chimeric
unconjugated
Fc fragment
Application Notes
The stated application concentrations are suggested starting points. Titration of the Folate Receptor beta antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. WB: 1:1000-1:2000
Restrictions
For Research Use only
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the Folate Receptor beta antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH . Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release.