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LBP antibody
LBP
Reactivity: Human
ELISA
Host: Mouse
Monoclonal
biG43
unconjugated
Product Details anti-LBP Antibody
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Target
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LBP
(Lipopolysaccharide Binding Protein (LBP))
Reactivity
All reactivities for LBP antibodies
Human
Host
All hosts for LBP antibodies
Mouse
Clonality
All clonalities for LBP antibodies
Monoclonal
Conjugate
All conjugates for LBP antibodies
This LBP antibody is un-conjugated
Application
All applications for LBP antibodies
ELISA
Specificity
Human LBP (Lipopolysaccaride binding protein). The antibody don't block LPS binding to membrane bound CD14.
Cross-Reactivity
Cow (Bovine), Dog (Canine), Horse (Equine), Rabbit
Cross-Reactivity (Details)
pork, rabbit, dog, horse, bovine LBP
Purification
Protein G affinity column
Immunogen
native human LBP
Clone
BiG43
Isotype
IgG2a
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Lyophilized
Reconstitution
Reconstitute with bidistilled water
Concentration
1 mg/mL
Buffer
PBS, pH 7.13
Preservative
Without preservative
Storage
-20 °C,-80 °C
Target Details for LBP
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Target
LBP
(Lipopolysaccharide Binding Protein (LBP))
Alternative Name
LBP (LBP Products )
Synonyms
BPIFD2 antibody, Bpifd2 antibody, Ly88 antibody, LPSBP antibody, LBP antibody, lipopolysaccharide binding protein antibody, lipopolysaccharide-binding protein antibody, LBP antibody, Lbp antibody, LOC100472839 antibody
Background
Background: Natural Lipopolysccaride Binding Protein (LBP) is a 58KD glycoprotein produced in liver. It binds at lipid A of LPS with high affinity (10-9M) and reduced the cellular LPS effects at CD14+ cells (IL1ß, IL6, TNFα). It acts as opsonin for GRAM negative cells, LPS, neutrophiles and granulocytes.
Molecular Weight
~58kDa
Gene ID
3929
NCBI Accession
NP_004130
UniProt
P18428
Pathways
TLR Signaling , Activation of Innate immune Response , Cellular Response to Molecule of Bacterial Origin , Positive Regulation of Immune Effector Process , Toll-Like Receptors Cascades , Monocarboxylic Acid Catabolic Process
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