SLC9A3R1 antibody (N-Term)

Catalog No. ABIN5671374

Product Details anti-SLC9A3R1 Antibody

Target: SLC9A3R1 (Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Cow, Dog, Zebrafish (Danio rerio), Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC9A3R1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AEKAGLLAGD RLVEVNGENV EKETHQQVVS RIRAALNAVR LLVVDPETDE

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against NHRF1. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human NHRF1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SLC9A3R1

Target: SLC9A3R1 (Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1))

Alternative Name: NHRF1 (SLC9A3R1 Products)

Synonyms: EBP50 antibody, NHERF antibody, NHERF-1 antibody, NHERF1 antibody, NPHLOP2 antibody, SLC9A3R1 antibody, cb895 antibody, slc9a3r2 antibody, wu:fd20a02 antibody, zgc:55541 antibody, zgc:77629 antibody, EBP-50 antibody, NHE-RF antibody, nherf antibody, nherf-1 antibody, nherf1 antibody, slc9a3r1 antibody, SLC9A3 regulator 1 antibody, microRNA 3615 antibody, solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1a antibody, solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 antibody, SLC9A3 regulator 1 S homeolog antibody, SLC9A3R1 antibody, MIR3615 antibody, slc9a3r1a antibody, Slc9a3r1 antibody, slc9a3r1.S antibody

Background: This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer.

Alias Symbols: SLC9A3R1, NHERF, NHERF1,

Protein Interaction Partner: ABCC4, UBC, MDM2, CKB, CAPN1, LDHAL6B, FTO, SMEK2, UBFD1, CNDP2, NANS, DAK, YWHAQ, GDA, NPEPPS, RPL23, YWHAZ, YWHAB, TGM2, SMS, RPS6KA3, LDHB, PDIA3, G6PD, ECHS1, CSE1L, CFTR, GNA11, PLCB1, EPHB1, PTEN, BCL10, ZNF468, gag-pol, MDH1, PALM2, PCYOX1, PPME1,

Protein Size: 358

Gene ID: 9368

NCBI Accession: NP_004243

UniProt: O14745

Pathways: Proton Transport, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, SARS-CoV-2 Protein Interactome