Human androgen receptor, 110 kDa protein in lysate of LNCP cell line.
Cross-Reactivity (Details)
Human
Characteristics
The antibody to androgen receptors binds to these proteins in nuclei of typical normal tissues. Over-expression may be observed in tumours like prostate carcinoma and osteosarcoma. For information transmission to the target cells male steroid hormones like Testosterone and DHT require a specific receptor. This specific receptor, called androgen receptor, is found in numerous human tissues like skin, mucous membranes, seminal vesicles, prostate gland and testis. Androgen receptors will also be found in human tumours like prostate carcinoma, osteosarcoma and others. In prostate carcinoma the clinical relevance has been proven by castration and androgen deprivation by Gn-RH-agonist and -antagonist treatment. In many cases androgen deprivation slows down tumour growth in androgen-dependent prostate carcinoma. Human androgen receptor, 110 kDa protein in lysate of LNCP cell line..
AR
Reactivity: Human, Mouse, Rat
IHC (p), IF (p)
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Heat pre-treatment of formalin-fixed tissue with Unmasking Fluid C or G ,Testis,IHC(C, P),60 min at RT,(liquid conc.) 1:5 - 1:20
Restrictions
For Research Use only
Format
Liquid
Buffer
stabilizing phosphate buffer pH 7.3. Contains 0.09 % sodium azide. The volume is sufficient for at least 100 immunohistochemical tests (100 μL working solution / test)
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.