This antibody detects endogenous level of total Glutamate receptor 2 (Precursor) protein.
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Immunogen
Glutamate receptor 2 (Precursor) (Ab-880) antibody was raised against a peptide sequence around aa.878~882 (I-E-S-V-K) derived from Human Glutamate receptor 2.
Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.