×
For best experience we recommend to activate Javascript in your browser.
MSK1 antibody (AA 374-378)
RPS6KA5
Reactivity: Human, Mouse, Rat
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MSK1 Antibody
(hide)
Target
See all MSK1 (RPS6KA5) Antibodies
MSK1 (RPS6KA5)
(Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5))
Binding Specificity
All epitopes for MSK1 antibodies
AA 374-378
Reactivity
All reactivities for MSK1 antibodies
Human, Mouse, Rat
Host
All hosts for MSK1 antibodies
Rabbit
Clonality
All clonalities for MSK1 antibodies
Polyclonal
Conjugate
All conjugates for MSK1 antibodies
This MSK1 antibody is un-conjugated
Application
All applications for MSK1 antibodies
Western Blotting (WB)
Specificity
This antibody detects endogenous level of total MSK1 protein.
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Immunogen
MSK1 (Ab-376) antibody was raised against a peptide sequence around aa.374~378 (G-Y-S-F-V) derived from Human MSK1.
Top Product
Discover our top product RPS6KA5 Primary Antibody
Alternatives
(show)
Application Details
(hide)
Application Notes
Western Blot: 1:500~1:1000
Restrictions
For Research Use only
Handling
(hide)
Format
Liquid
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store antibody at -20°C for up to one year.
Target Details for MSK1
(hide)
Target
MSK1 (RPS6KA5)
(Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5))
Alternative Name
MSK1 (RPS6KA5 Products )
Synonyms
MSK1 antibody, MSPK1 antibody, RLPK antibody, 3110005L17Rik antibody, 6330404E13Rik antibody, AI854034 antibody, Msk1 antibody, ribosomal protein S6 kinase A5 antibody, ribosomal protein S6 kinase, polypeptide 5 antibody, RPS6KA5 antibody, Rps6ka5 antibody
Background
Serine/threonine kinase required for the mitogen or stress-induced phosphorylation of the transcription factors CREB (cAMP response element-binding protein) and ATF1 (activating transcription factor-1). Essential role in the control of RELA transcriptional activity in response to TNF. Directly represses transcription via phosphorylation of 'Ser-1' of histone H2A. Phosphorylates 'Ser-10' of histone H3 in response to mitogenics, stress stimuli and epidemal growth-factor (EGF), which results in the transcriptional activation of several immediate early genes, including proto-oncogenes c-fos/FOS and c-jun/JUN. May also phosphorylate 'Ser-28' of histone H3. Mediates the mitogen- and stress-induced phosphorylation of high mobility group protein 14 (HMG-14).
Molecular Weight
90 kDa
Gene ID
9252
NCBI Accession
NP_004746
UniProt
O75582
Pathways
MAPK Signaling , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Activation of Innate immune Response , Toll-Like Receptors Cascades
Recently viewed
(hide)