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RUNX1 antibody (AA 6-10)
RUNX1
Reactivity: Human, Mouse, Rat
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-RUNX1 Antibody
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Target
See all RUNX1 Antibodies
RUNX1
(Runt-Related Transcription Factor 1 (RUNX1))
Binding Specificity
All epitopes for RUNX1 antibodies
AA 6-10
Reactivity
All reactivities for RUNX1 antibodies
Human, Mouse, Rat
Host
All hosts for RUNX1 antibodies
Rabbit
Clonality
All clonalities for RUNX1 antibodies
Polyclonal
Conjugate
All conjugates for RUNX1 antibodies
This RUNX1 antibody is un-conjugated
Application
All applications for RUNX1 antibodies
Western Blotting (WB)
Specificity
This antibody detects endogenous level of total AML1(RUNX1) protein.
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Immunogen
AML1 (RUNX1) antibody was raised against a peptide sequence around aa.6~10 (D-A-S-T-S) derived from Human AML1 (RUNX1).
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Discover our top product RUNX1 Primary Antibody
Alternatives
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Application Details
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Application Notes
Western Blot: 1:500~1:1000
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store antibody at -20°C for up to one year.
Target Details for RUNX1
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Target
RUNX1
(Runt-Related Transcription Factor 1 (RUNX1))
Alternative Name
AML1 (RUNX1 Products )
Synonyms
RUNX1 antibody, runx1 antibody, AI462102 antibody, AML1 antibody, Cbfa2 antibody, Pebp2a2 antibody, Pebpa2b antibody, AML1-EVI-1 antibody, AMLCR1 antibody, CBFA2 antibody, EVI-1 antibody, PEBP2aB antibody, runxa antibody, Runx-1 antibody, XAML antibody, Xaml1 antibody, aml antibody, aml-1 antibody, aml1 antibody, aml1-evi-1 antibody, amlcr1 antibody, cbfa2 antibody, evi-1 antibody, pebp2ab antibody, Aml1 antibody, uncharacterized LOC473981 antibody, runt-related transcription factor antibody, runt related transcription factor 1 antibody, runt-related transcription factor 1 antibody, runt related transcription factor 1 L homeolog antibody, LOC473981 antibody, runt antibody, Runx1 antibody, RUNX1 antibody, runx1 antibody, runx1.L antibody
Background
CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. The alpha subunit binds DNA and appears to have a role in the development of normal hematopoiesis. Isoform AML-1L interferes with the transactivation activity of RUNX1. Acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the mouse BLK promoter. Inhibits MYST4-dependent transcriptional activation.
Molecular Weight
55 kDa
Gene ID
861
NCBI Accession
NP_001116079
UniProt
Q01196
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