This antibody detects endogenous level of ATF-2 only when phosphorylated at serine 112 or 94.
Purification
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Immunogen
ATF2 (Phospho-Ser112 or 94) antibody was raised against a peptide sequence around phosphorylation site of serine 112 or 94 (D-L-S (p) -P-L) derived from Human ATF2.
Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2-c-Jun complex.