RAN antibody
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- Target See all RAN Antibodies
- RAN (RAN, Member RAS Oncogene Family (RAN))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RAN antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
- Immunogen
- RAN, member RAS oncogene family
- Isotype
- IgG
- Top Product
- Discover our top product RAN Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab07100( RAN Antibody) at dilution of 1:1000
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- RAN (RAN, Member RAS Oncogene Family (RAN))
- Alternative Name
- RAN (RAN Products)
- Synonyms
- ARA24 antibody, Gsp1 antibody, TC4 antibody, ran antibody, ara24 antibody, gsp1 antibody, ran-1 antibody, tc4 antibody, RAN antibody, RANP1 antibody, AAF30287 antibody, CG1404 antibody, Dmel\CG1404 antibody, Ran antibody, dran antibody, l(1)G0075 antibody, ran10A antibody, fc16b04 antibody, wu:fc16b04 antibody, RAN, member RAS oncogene family antibody, RAN, member RAS oncogene family S homeolog antibody, CG1404 gene product from transcript CG1404-RC antibody, RAN antibody, Ran antibody, ran.S antibody, ran antibody
- Background
- Synonyms:ARA24 Background:GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle(By similarity). The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. Acts as a negative regulator of the kinase activity of VRK1 and VRK2. Enhances AR-mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases.
- Gene ID
- 5901
- UniProt
- P62826
- Pathways
- Regulatory RNA Pathways, Intracellular Steroid Hormone Receptor Signaling Pathway, Protein targeting to Nucleus
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