SOCS6 antibody

Catalog No. ABIN5698499

Product Details anti-SOCS6 Antibody

Target: SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOCS6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Immunogen: suppressor of cytokine signaling 6

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for SOCS6

Target: SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))

Alternative Name: SOCS6 (SOCS6 Products)

Synonyms: CIS-4 antibody, CIS4 antibody, HSPC060 antibody, SOCS-4 antibody, SOCS-6 antibody, SOCS4 antibody, SSI4 antibody, STAI4 antibody, STATI4 antibody, socs6 antibody, MGC81477 antibody, SOCS6 antibody, 1500012M23Rik antibody, 5830401B18Rik antibody, AI447482 antibody, Cis4 antibody, Cish4 antibody, Socs4 antibody, socs6l antibody, zgc:64107 antibody, wu:fb77f06 antibody, suppressor of cytokine signaling 6 antibody, suppressor of cytokine signaling 6 L homeolog antibody, suppressor of cytokine signaling antibody, suppressor of cytokine signaling 6b antibody, SOCS6 antibody, Socs6 antibody, socs6.L antibody, socs6 antibody, socs6b antibody

Background: Synonyms:CIS4, SOCS4 Background:SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of a SCF-like ECS(Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins(By similarity). Regulates KIT degradation by ubiquitination of the tyrosine-phosphorylated receptor.

Gene ID: 9306

UniProt: O14544

Pathways: JAK-STAT Signaling, Carbohydrate Homeostasis