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TRIB3 antibody

TRIB3 Reactivity: Human, Mouse, Rat WB, ELISA, IP Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5699082
  • Target See all TRIB3 Antibodies
    TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))
    Reactivity
    • 64
    • 27
    • 22
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 71
    • 5
    Rabbit
    Clonality
    • 73
    • 3
    Polyclonal
    Conjugate
    • 37
    • 7
    • 6
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRIB3 antibody is un-conjugated
    Application
    • 53
    • 42
    • 14
    • 14
    • 13
    • 13
    • 11
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    Immunogen
    tribbles homolog 3 (Drosophila)
    Isotype
    IgG
    Top Product
    Discover our top product TRIB3 Primary Antibody
  • Application Notes
    WB:1:500-1:5000,IP:1:200-1:2000
    Comment

    mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab08966(TRIB3 antibody) at dilution of 1:600

    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze / thaw cycles.
    Storage
    -20 °C
    Expiry Date
    12 months
  • Target
    TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))
    Alternative Name
    TRIB3 (TRIB3 Products)
    Synonyms
    zgc:76966 antibody, TRIB3 antibody, C20orf97 antibody, NIPK antibody, SINK antibody, SKIP3 antibody, TRB3 antibody, Ifld2 antibody, Nipk antibody, TRB-3 antibody, Trb3 antibody, tribbles pseudokinase 3 antibody, trib3 antibody, TRIB3 antibody, Trib3 antibody
    Background
    Synonyms:C20orf97, NIPK, SINK, SKIP3, TRB 3, TRB3, TRIB3, Tribbles homolog 3 Background:Disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. May bind directly to and mask the 'Thr-308' phosphorylation site in AKT1. Binds to ATF4 and inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity. Interacts with MAPK kinases and regulates activation of MAP kinases. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells. Does not display kinase activity. Inhibits the transcriptional activity of DDIT3/CHOP and is involved in DDIT3/CHOP-dependent cell death during ER stress. Can inhibit APOBEC3A editing of nuclear DNA.
    Molecular Weight
    42kDa
    Gene ID
    57761
    UniProt
    Q96RU7
    Pathways
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
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