NUMB antibody

Catalog No. ABIN5699503

Product Details anti-NUMB Antibody

Target: NUMB (Numb Homolog (NUMB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUMB antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Immunogen: numb homolog (Drosophila)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for NUMB

Target: NUMB (Numb Homolog (NUMB))

Alternative Name: NUMB (NUMB Products)

Synonyms: C14orf41 antibody, S171 antibody, c14_5527 antibody, Nb antibody, NUMB, endocytic adaptor protein antibody, numb homolog (Drosophila) antibody, NUMB antibody, Numb antibody, numb antibody

Background: Synonyms: Background:Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells(RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone(SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.

Molecular Weight: 66-72 kDa

Gene ID: 8650

UniProt: P49757

Pathways: Cell-Cell Junction Organization