DREAM antibody

Catalog No. ABIN5700773

Product Details anti-DREAM Antibody

Target: DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DREAM antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogen: Kv channel interacting protein 3, calsenilin

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

human brain tissue were subjected to SDS PAGE followed by western blot with FNab04488(KCNIP3 antibody) at dilution of 1:500

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for DREAM

Target: DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))

Alternative Name: KCNIP3 (KCNIP3 Products)

Synonyms: CSEN antibody, DREAM antibody, KCHIP3 antibody, 4933407H12Rik antibody, AI413860 antibody, Csen antibody, KChIP3 antibody, R74849 antibody, Dream antibody, rKChIP3 antibody, csen antibody, im:7145308 antibody, kcnip3 antibody, zgc:73306 antibody, KCNIP3 antibody, potassium voltage-gated channel interacting protein 3 antibody, Kv channel-interacting protein 4 antibody, calsenilin antibody, Kv channel interacting protein 3, calsenilin antibody, Kv channel interacting protein 3b, calsenilin antibody, KCNIP3 antibody, LOC5568664 antibody, CpipJ_CPIJ002549 antibody, Tsp_05009 antibody, Kcnip3 antibody, kcnip3b antibody, kcnip3 antibody

Background: Synonyms:CSEN, DREAM, KCHIP3 Background:Calcium-dependent transcriptional repressor that binds to the DRE element of genes including PDYN and FOS. Affinity for DNA is reduced upon binding to calcium and enhanced by binding to magnesium. Seems to be involved in nociception(By similarity). Regulatory subunit of Kv4/D(Shal)-type voltage-gated rapidly inactivating A-type potassium channels, such as KCND2/Kv4.2 and KCND3/Kv4.3. Modulates channel expression at the cell membrane, gating characteristics, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. May play a role in the regulation of PSEN2 proteolytic processing and apoptosis. Together with PSEN2 involved in modulation of beta-amyloid formation.

Molecular Weight: 29 kDa

Gene ID: 30818

UniProt: Q9Y2W7