TRF1 antibody

Catalog No. ABIN5701599

Product Details anti-TRF1 Antibody

Target: TRF1 (TERF1) (Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Immunogen: telomeric repeat binding factor (NIMA-interacting) 1

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab08597(TERF1 antibody) at dilution of 1:500

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for TRF1

Target: TRF1 (TERF1) (Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))

Alternative Name: TERF1 (TERF1 Products)

Synonyms: PIN2 antibody, TRBF1 antibody, TRF antibody, TRF1 antibody, hTRF1-AS antibody, t-TRF1 antibody, wu:fb74c04 antibody, TERF1 antibody, DKFZp459A0713 antibody, Pin2 antibody, Trbf1 antibody, Trf1 antibody, terf1 antibody, trf1 antibody, telomeric repeat binding factor 1 antibody, telomeric repeat binding factor (NIMA-interacting) 1 antibody, telomeric repeat binding factor (NIMA-interacting) 1 L homeolog antibody, TERF1 antibody, Terf1 antibody, terf1 antibody, Trf1 antibody, terf1.L antibody

Background: Synonyms:PIN2, TRBF1, TRF, TRF1 Background:This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products.

Gene ID: 7013

UniProt: P54274

Pathways: Cell Division Cycle, Telomere Maintenance, Hormone Transport, Chromatin Binding, Regulation of Cell Size, Positive Regulation of Endopeptidase Activity