RGS7 antibody

Catalog No. ABIN5703291

Product Details anti-RGS7 Antibody

Target: RGS7 (Regulator of G-Protein Signaling 7 (RGS7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogen: regulator of G-protein signaling 7

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

SH-SY5Y cells were subjected to SDS PAGE followed by western blot with FNab07273(RGS7 antibody) at dilution of 1:500

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for RGS7

Target: RGS7 (Regulator of G-Protein Signaling 7 (RGS7))

Alternative Name: RGS7 (RGS7 Products)

Synonyms: zgc:92793 antibody, RGS7 antibody, regulator of G-protein signaling 7 antibody, regulator of G protein signaling 7a antibody, regulator of G protein signaling 7 antibody, Regulator of G protein Signaling antibody, RGS7 antibody, rgs7a antibody, CpipJ_CPIJ014798 antibody, Tsp_03415 antibody, rgs-7 antibody, Rgs7 antibody

Background: Synonyms: Background:Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form(PubMed:10521509, PubMed:10862767). The RGS7/GNB5 dimer enhances GNAO1 GTPase activity(PubMed:10521509). May play a role in synaptic vesicle exocytosis(PubMed:12659861). Modulates the activity of potassium channels that are activated by GNAO1 in response to muscarinic acetylcholine receptor M2/CHRM2 signaling(PubMed:15897264).

Gene ID: 6000

UniProt: P49802

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling