EPH Receptor B4 antibody

Catalog No. ABIN5703803

Product Details anti-EPH Receptor B4 Antibody

Target: EPH Receptor B4 (EPHB4)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPH Receptor B4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Immunogen: EPH receptor B4

Isotype: IgG

Application Details

Application Notes: WB : 1:500-1:5000 IHC : 1:20-1:200

Comment:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab02807( EPHB4 Antibody) at dilution of 1:1000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for EPH Receptor B4

Target: EPH Receptor B4 (EPHB4)

Alternative Name: EPHB4 (EPHB4 Products)

Synonyms: HTK antibody, MYK1 antibody, TYRO11 antibody, htk antibody, myk1 antibody, ephB4a antibody, tyro11 antibody, ephb4b antibody, MGC130997 antibody, AI042935 antibody, Htk antibody, MDK2 antibody, Myk1 antibody, Tyro11 antibody, cb646 antibody, ephB4 antibody, rtk5 antibody, EphB-rtk8 antibody, cb417 antibody, rtk8 antibody, EPH receptor B4 antibody, EPH receptor B4 L homeolog antibody, EPH receptor B4 S homeolog antibody, Eph receptor B4 antibody, eph receptor B4a antibody, eph receptor B4b antibody, EPHB4 antibody, ephb4.L antibody, ephb4.S antibody, ephb4 antibody, Ephb4 antibody, ephb4a antibody, ephb4b antibody

Background: Synonyms:EPH receptor B4, EPHB4, Ephrin type B receptor 4, HTK, MYK1, TYRO11, Tyrosine protein kinase TYRO11 Background:Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation form EFNB2-expressing cells. Plays also a role in postnatal blood vessel remodeling, morphogenesis and permeability and is thus important in the context of tumor angiogenesis.

Molecular Weight: 110 kDa

Gene ID: 2050

UniProt: P54760

Pathways: RTK Signaling