IL12RB1 antibody

Catalog No. ABIN5703864

Product Details anti-IL12RB1 Antibody

Target: IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL12RB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Immunogen: interleukin 12 receptor, beta 1

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for IL12RB1

Target: IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))

Alternative Name: IL12RB1 (IL12RB1 Products)

Synonyms: Il12rb antibody, IL12RB1 antibody, IL-12R antibody, CD212 antibody, IL-12R-BETA1 antibody, IL12RB antibody, IL-12R[b] antibody, interleukin 12 receptor subunit beta 1 antibody, interleukin 12 receptor, beta 1 antibody, Il12rb1 antibody, IL12RB1 antibody

Background: Synonyms:IL12R, IL12RB Background:Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.

Molecular Weight: 100 kDa

Gene ID: 3594

UniProt: P42701

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation