PPP2R1B antibody

Catalog No. ABIN5704178

Product Details anti-PPP2R1B Antibody

Target: PPP2R1B (Protein Phosphatase 2, Regulatory Subunit A, beta (PPP2R1B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP2R1B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Immunogen: protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for PPP2R1B

Target: PPP2R1B (Protein Phosphatase 2, Regulatory Subunit A, beta (PPP2R1B))

Alternative Name: PPP2R1B (PPP2R1B Products)

Synonyms: 2410091N08Rik antibody, AI790395 antibody, PP2A-Abeta antibody, PR65B antibody, protein phosphatase 2, regulatory subunit A, beta antibody, protein phosphatase 2 scaffold subunit Abeta antibody, protein phosphatase 2 scaffold subunit A beta antibody, protein phosphatase 2 regulatory subunit A, beta S homeolog antibody, Ppp2r1b antibody, PPP2R1B antibody, ppp2r1b.S antibody

Background: Synonyms: Background:This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described.

Gene ID: 5519

UniProt: P30154

Pathways: PI3K-Akt Signaling, Mitotic G1-G1/S Phases, Hepatitis C, Toll-Like Receptors Cascades