NEUROD1 antibody
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- Target See all NEUROD1 Antibodies
- NEUROD1 (Neuronal Differentiation 1 (NEUROD1))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NEUROD1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Immunogen
- neurogenic differentiation 1
- Isotype
- IgG
- Top Product
- Discover our top product NEUROD1 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Y79 cells were subjected to SDS PAGE followed by western blot with FNab05674(NEUROD1 antibody) at dilution of 1:200
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- NEUROD1 (Neuronal Differentiation 1 (NEUROD1))
- Alternative Name
- NEUROD1 (NEUROD1 Products)
- Synonyms
- BETA2 antibody, BHF-1 antibody, MODY6 antibody, NEUROD antibody, bHLHa3 antibody, Neurod antibody, neurod antibody, XNeuroD antibody, MGC82572 antibody, NEUROD1 antibody, ND1 antibody, beta2 antibody, bhf-1 antibody, neuro-D antibody, nrd antibody, neuroD antibody, neurod1 antibody, Beta2 antibody, neuronal differentiation 1 antibody, neurogenic differentiation 1 antibody, neuronal differentiation 1 S homeolog antibody, neuronal differentiation 1 L homeolog antibody, NEUROD1 antibody, Neurod1 antibody, neurod1.S antibody, neurod1 antibody, neurod1.L antibody
- Background
- Synonyms:BHLHA3, NEUROD Background:Acts as a transcriptional activator: mediates transcriptional activation by binding to E box-containing promoter consensus core sequences 5'-CANNTG-3'. Associates with the p300/CBP transcription coactivator complex to stimulate transcription of the secretin gene as well as the gene encoding the cyclin-dependent kinase inhibitor CDKN1A. Contributes to the regulation of several cell differentiation pathways, like those that promote the formation of early retinal ganglion cells, inner ear sensory neurons, granule cells forming either the cerebellum or the dentate gyrus cell layer of the hippocampus, endocrine islet cells of the pancreas and enteroendocrine cells of the small intestine. Together with PAX6 or SIX3, is required for the regulation of amacrine cell fate specification. Also required for dendrite morphogenesis and maintenance in the cerebellar cortex. Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis(By similarity).
- Molecular Weight
- 50 kDa
- Gene ID
- 4760
- UniProt
- Q13562
- Pathways
- Dopaminergic Neurogenesis, Hormone Transport, Carbohydrate Homeostasis
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