ATF2 antibody (pSer112)

Catalog No. ABIN5955769

Product Details anti-ATF2 Antibody

Target: ATF2 (Activating Transcription Factor 2 (ATF2))

Binding Specificity: pSer112

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Activating transcription factor 2,Activating transcription factor 2 splice variant ATF2 var2,ATF 2,Atf-2,Atf2,ATF2 protein,ATF2,cAMP Response Element Binding Protein 2,cAMP response element binding protein CRE BP1,cAMP response element-binding protein CRE-BP1,cAMP responsive element binding protein 2,formerly,cAMP-dependent transcription factor ATF-2,cAMP-responsive element-binding protein 2,CRE BP1,CRE-BP,CREB 2,CREB-2,CREB2,CREBP1,Cyclic AMP dependent transcription factor ATF 2,Cyclic AMP-dependent transcription factor ATF-2,Cyclic AMP-responsive element-binding protein 2,D130078H02Rik,D18875,HB 16,HB16,Histone acetyltransferase ATF2,MGC105211,MGC105222,MGC111558,MGC142504,mXBP,MXBP protein,Tg(Gzma-Klra1)7Wum,TREB 7,TREB7

Purification: Affinity purification

Immunogen: Synthesized peptide derived from human ATF-2 around the phosphorylation site of Ser112

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:100-1:300, IP 1:200-1:500, ELISA 1:20000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ATF2

Target: ATF2 (Activating Transcription Factor 2 (ATF2))

Alternative Name: ATF-2 (ATF2 Products)

Synonyms: CRE-BP1 antibody, CREB2 antibody, HB16 antibody, TREB7 antibody, CG12850 antibody, CG3749 antibody, dATF-2 antibody, DmelCG30420 antibody, CG30420 antibody, CHN1 antibody, Atf-2 antibody, CRE-BP antibody, Creb2 antibody, D130078H02Rik antibody, D18875 antibody, Tg(Gzma-Klra1)7Wum antibody, mXBP antibody, atf2-A antibody, atf2l antibody, activating transcription factor 2 antibody, Activating transcription factor-2 antibody, activating transcription factor 2 S homeolog antibody, ATF2 antibody, Atf-2 antibody, Atf2 antibody, atf2.S antibody, atf2 antibody

Background: Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2/JUN complex.

Molecular Weight: 52kDa

Gene ID: 1386

UniProt: P15336

Pathways: MAPK Signaling, RTK Signaling, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades