IGF2R antibody (C-Term)

Catalog No. ABIN5956192

Product Details anti-IGF2R Antibody

Target: IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGF2R antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: 300 kDa mannose 6 phosphate receptor,300 kDa mannose 6-phosphate receptor,Cation independent mannose 6 phosphate receptor,Cation-independent mannose-6-phosphate receptor,CD222,CD222 antigen,CI Man 6 P receptor,CI Man-6-P receptor,CI MPR,CI-M6PR,CI-MPR,CIMPR,IGF 2 receptor,IGF 2R,IGF II receptor,IGF-II receptor,IGF2 receptor,Igf2r,Insulin like growth factor 2 receptor,Insulin like growth factor II receptor,Insulin-like growth factor 2 receptor,Insulin-like growth factor II receptor,M6P R,M6P/IGF2 receptor,M6P/IGF2R,M6PR,mannose 6 phosphate receptor,mannose 6 phosphate receptor,cation independent,MPR 300,MPR300,MPRI,MPRI

Purification: Affinity purification

Immunogen: Synthesized peptide derived from the C-terminal region of human IGF-IIR.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, ELISA 1:20000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IGF2R

Target: IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

Alternative Name: IGF-IIR (IGF2R Products)

Synonyms: CD222 antibody, CIMPR antibody, M6P-R antibody, MPR1 antibody, MPRI antibody, AI661837 antibody, CI-MPR antibody, M6P/IGF2R antibody, Mpr300 antibody, mpri antibody, cd222 antibody, cimpr antibody, m6p-r antibody, insulin like growth factor 2 receptor antibody, insulin-like growth factor 2 receptor antibody, IGF2R antibody, Igf2r antibody, igf2r antibody

Background: This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.

Molecular Weight: 274kDa

Gene ID: 3482

UniProt: P11717