Western Blotting (WB), ELISA, Immunofluorescence (IF)
Specificity
Hbo 1,HBO1,HBOa,Histone acetyltransferase binding to hORC1,Histone acetyltransferase binding to ORC1,Histone acetyltransferase KAT7,Histone acetyltransferase MYST2,K(lysine) acetyltransferase 7,KAT 7,KAT7,Lysine acetyltransferase 7,MOZ,MOZ YBF2/SAS3 SAS2 and TIP60 protein,MOZ,YBF2/SAS3,SAS2 and TIP60 protein 2,MYST 2,MYST histone acetyltransferase 2,MYST protein 2,MYST-2,MYST2,MYST2,SAS 2,SAS2 and TIP60 protein 2,TIP60 protein 2,YBF2/SAS3,ZC2HC7
Purification
Affinity purification
Immunogen
Synthesized peptide derived from the Internal region of human HBO1
The protein encoded by this gene is part of the multimeric HBO1 complex, which possesses histone H4-specific acetyltransferase activity. This activity is required for functional replication origins and is involved in transcriptional activation of some genes. In both cases, the acetylation of histone H4 helps unfold chromatin so that the DNA can be accessed and replicated or transcribed.