MCL-1 antibody (pSer159)

Catalog No. ABIN5957044

Product Details anti-MCL-1 Antibody

Target: MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))

Binding Specificity: pSer159

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCL-1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Specificity: Bcl 2 related protein EAT/mcl1,Bcl-2-like protein 3,Bcl-2-related protein EAT/mcl1,BCL2 related,Bcl2-L-3,BCL2L3,EAT,Induced myeloid leukemia cell differentiation protein Mcl 1,Induced myeloid leukemia cell differentiation protein Mcl-1,MCL 1,MCL1,MCL1-ES,mcl1/EAT,MCL1,MCL1L,MCL1S,MGC104264,MGC1839,Myeloid Cell Leukemia 1,Myeloid cell leukemia ES,Myeloid cell leukemia sequence 1,Myeloid cell leukemia sequence 1 BCL2 related,Myeloid cell leukemia sequence 1 isoform 1,OTTHUMP00000032794,OTTHUMP00000032795,TM

Purification: Affinity purification

Immunogen: Synthesized peptide derived from human Mcl-1 around the phosphorylation site of S159.

Isotype: IgG

Application Details

Application Notes: IF 1:200-1:1000, ELISA 1:10000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide,0.5 % BSA and 50 % glycerol  pH 7.4.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MCL-1

Target: MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))

Alternative Name: Mcl-1 (MCL1 Products)

Synonyms: BCL2L3 antibody, EAT antibody, MCL1-ES antibody, MCL1L antibody, MCL1S antibody, Mcl-1 antibody, TM antibody, bcl2-L-3 antibody, mcl1/EAT antibody, AW556805 antibody, mcl-1 antibody, fb72f02 antibody, wu:fb70a08 antibody, wu:fb72f02 antibody, zfMLP1 antibody, zfMcl-1a antibody, zgc:109835 antibody, zgc:109763 antibody, E3 antibody, E3-2 antibody, RNE3 antibody, RNU107 antibody, SNORA63A antibody, elF-4AII antibody, MCL1, BCL2 family apoptosis regulator antibody, myeloid cell leukemia sequence 1 antibody, MCL1, BCL2 family apoptosis regulator a antibody, MCL1, BCL2 family apoptosis regulator b antibody, small nucleolar RNA, H/ACA box 63 antibody, MCL1 antibody, Mcl1 antibody, mcl1a antibody, mcl1b antibody, SNORA63 antibody

Background: This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.

Molecular Weight: 37kDa

Gene ID: 4170

UniProt: Q07820

Pathways: MAPK Signaling