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PKC zeta antibody (pThr560)
PRKCZ
Reactivity: Human, Mouse, Rat, Monkey
WB, ELISA, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PKC zeta Antibody
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Target
See all PKC zeta (PRKCZ) Antibodies
PKC zeta (PRKCZ)
(Protein Kinase C, zeta (PRKCZ))
Binding Specificity
All epitopes for PKC zeta antibodies
pThr560
Reactivity
All reactivities for PKC zeta antibodies
Human, Mouse, Rat, Monkey
Host
All hosts for PKC zeta antibodies
Rabbit
Clonality
All clonalities for PKC zeta antibodies
Polyclonal
Conjugate
All conjugates for PKC zeta antibodies
This PKC zeta antibody is un-conjugated
Application
All applications for PKC zeta antibodies
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
14-3-3-zetaisoform,AI098070,aPKCzeta,C80388,EC 2.7.11.13,KPCZ,nPKC zeta,nPKC-zeta,OTTHUMP00000001368,OTTHUMP00000044160,PKC 2,PKC ZETA,PKC2,Pkcz,PKCZETA,PKM-zeta,included,PRKCZ,Protein kinase C zeta,Protein kinase C zeta form,Protein kinase C zeta type,r14-3-3,R74924,zetaPKC
Purification
Affinity purification
Immunogen
Synthesized peptide derived from human PKC zeta around the phosphorylation site of T560.
Isotype
IgG
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Discover our top product PRKCZ Primary Antibody
Alternatives
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Application Details
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Application Notes
WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
Restrictions
For Research Use only
Handling
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Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide,0.5 % BSA and 50 % glycerol pH 7.4.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for PKC zeta
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Target
PKC zeta (PRKCZ)
(Protein Kinase C, zeta (PRKCZ))
Alternative Name
PKC zeta (PRKCZ Products )
Synonyms
TPKC antibody, PKCzeta antibody, prkcz-A antibody, pkc-zeta antibody, PRKCZ antibody, pkc2 antibody, PKC-ZETA antibody, PKC2 antibody, AI098070 antibody, C80388 antibody, Pkcz antibody, R74924 antibody, aPKCzeta antibody, zetaPKC antibody, 14-3-3-zetaisoform antibody, r14-3-3 antibody, pkcz antibody, si:ch211-150o23.4 antibody, protein kinase C zeta L homeolog antibody, protein kinase C zeta antibody, protein kinase C, zeta antibody, prkcz.L antibody, PRKCZ antibody, prkcz antibody, Prkcz antibody
Background
This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Phosphorylates 'Ser-311' of RELA subunit of NF-kappa-B.PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. Subunit of a quaternary complex that plays a central role in epithelial cell polarization.
Molecular Weight
68kDa
Gene ID
5590
UniProt
Q05513
Pathways
NF-kappaB Signaling , RTK Signaling , Myometrial Relaxation and Contraction , Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Synaptic Membrane , Production of Molecular Mediator of Immune Response , CXCR4-mediated Signaling Events , Thromboxane A2 Receptor Signaling
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