IL-6 antibody

Catalog No. ABIN5959615

Product Details anti-IL-6 Antibody

Target: IL-6 (IL6) (Interleukin 6 (IL6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Interleukin BSF 2,B cell differentiation factor,B cell stimulatory factor 2,B-cell stimulatory factor 2,BSF 2,BSF-2,BSF2,CDF,CTL differentiation factor,Hepatocyte stimulatory factor,HGF,HSF,Hybridoma growth factor,Hybridoma growth factor Interferon beta-2,IFN-beta-2,IFNB2,IL 6,IL-6,IL6,IL6,Interferon beta 2,Interferon beta-2,Interleukin 6,Interleukin 6 (interferon beta 2),Interleukin BSF 2,Interleukin-6

Purification: Affinity purification

Immunogen: Synthesized peptide derived from the Internal region of human IL-6.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000-1:20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-IL-6 antibody (ABIN5959615)

Wang, Ma, Wang, Zhu, Yang, Zeng, Yuan, Liu, Gao, Chen, Jia: "Triptonide inhibits the pathological functions of gastric cancer-associated fibroblasts." in: Biomedicine & pharmacotherapy, Vol. 96, pp. 757-767, (2018) (PubMed).

Target Details for IL-6

Target: IL-6 (IL6) (Interleukin 6 (IL6))

Alternative Name: IL6 (IL6 Products)

Synonyms: BSF2 antibody, HGF antibody, HSF antibody, IFNB2 antibody, IL-6 antibody, Il-6 antibody, ILg6 antibody, Ifnb2 antibody, il6 antibody, CHIL-6 antibody, interleukin 6 antibody, interleukin-6 antibody, IL6 antibody, Il6 antibody, il-6 antibody, IL-6 antibody

Background: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoeitic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance.

Molecular Weight: 21-30kDa

Gene ID: 3569

UniProt: P05231

Pathways: TLR Signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome