SLUG antibody

Catalog No. ABIN5962818

Product Details anti-SLUG Antibody

Target: SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLUG antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Recombinant protein of human SNAI2

Isotype: IgG

Application Details

Application Notes: IHC 1:50 - 1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SLUG

Target: SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))

Alternative Name: SNAI2 (SNAI2 Products)

Synonyms: Slug antibody, Slugh antibody, Snail2 antibody, snail family transcriptional repressor 2 antibody, snail family zinc finger 2 antibody, Snai2 antibody

Background:

Synonyms: MGC10182,Neural crest transcription factor Slug,Protein snail homolog 2,Slug (chicken homolog) zinc finger protein,Slug homolog zinc finger protein,Slug zinc finger protein,SLUGH,SLUGH 1,SLUGH1,SNAI 2,Snai2,SNAI2,Snail 2,Snail homolog 2,Snail2,WS 2D,WS2D,Zinc finger protein SLUG,Zinc finger protein SNAI2

Background: This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 29kDa

Gene ID: 6591

UniProt: O43623