Kallikrein 7 antibody
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- Target See all Kallikrein 7 (KLK7) Antibodies
- Kallikrein 7 (KLK7)
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Kallikrein 7 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human KLK7
- Isotype
- IgG
- Top Product
- Discover our top product KLK7 Primary Antibody
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- Application Notes
- WB 1:500 - 1:2000
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Kallikrein 7 (KLK7)
- Alternative Name
- KLK7 (KLK7 Products)
- Synonyms
- Prss6 antibody, SCCE antibody, PRSS6 antibody, hK7 antibody, kallikrein related-peptidase 7 (chymotryptic, stratum corneum) antibody, kallikrein-related peptidase 7 antibody, kallikrein related peptidase 7 antibody, Klk7 antibody, KLK7 antibody
- Background
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Synonyms: Chymotryptic stratum corneum,hK 7,hK7,hSCCE,Kallikrein 7 (chymotryptic stratum corneum),Kallikrein related peptidase 7,Kallikrein-7,Kallikrein7,KLK 7,Klk7,KLK7,Protease serine 6,PRSS 6,PRSS6,SCCE,Serine protease 6,Signal protein,Stratum corneum chymotryptic enzyme
Background: This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19.
- Molecular Weight
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Observed_MW: 30kDa
Calculated_MW: 19kDa/27kDa
- Gene ID
- 5650
- UniProt
- P49862
- Pathways
- Complement System
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