NCF1 antibody

Catalog No. ABIN5963816

Product Details anti-NCF1 Antibody

Target: NCF1 (Neutrophil Cytosol Factor 1 (NCF1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCF1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human NCF1

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NCF1

Target: NCF1 (Neutrophil Cytosol Factor 1 (NCF1))

Alternative Name: p47-phox (NCF1 Products)

Synonyms: NCF1A antibody, NOXO2 antibody, SH3PXD1A antibody, p47phox antibody, Ncf-1 antibody, p47 antibody, neutrophil cytosolic factor 1 antibody, NCF1 antibody, Ncf1 antibody

Background:

Synonyms: 47 kDa autosomal chronic granulomatous disease protein,47 kDa neutrophil oxidase factor,NADPH oxidase organizer 2,NCF 47K,NCF-1,NCF-47K,Ncf1,NCF1,Neutrophil cytosol factor 1,Neutrophil cytosolic factor 1,neutrophil cytosolic factor 1,(chronic granulomatous disease,autosomal 1),Neutrophil NADPH oxidase factor 1,Nox organizer 2,Nox organizing protein 2,Nox-organizing protein 2,NOXO2,p47 phox,p47-phox,SH3 and PX domain containing protein 1A,SH3 and PX domain-containing protein 1A,SH3PXD1A

Background: The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease.

Molecular Weight:

Observed_MW: 45kDa

Calculated_MW: 30kDa/44kDa

Gene ID: 653361

UniProt: P14598

Pathways: PI3K-Akt Signaling